Smarca5-mediated epigenetic programming facilitates fetal HSPC development in vertebrates

Nascent hematopoietic stem and progenitor cells (HSPCs) acquire definitive hematopoietic characteristics only when they develop into fetal HSPCs; however, the mechanisms underlying fetal HSPC development are poorly understood. Here, we profiled the chromatin accessibility and transcriptional feature...

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Guardat en:
Dades bibliogràfiques
Publicat a:Blood
Autors principals: Ding, Yanyan, Wang, Wen, Ma, Dongyuan, Liang, Guixian, Kang, Zhixin, Xue, Yuanyuan, Zhang, Yifan, Wang, Lu, Heng, Jian, Zhang, Yong, Liu, Feng
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820875/
https://ncbi.nlm.nih.gov/pubmed/32756943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005219
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