The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development

BACKGROUND: Cryptophthalmos is characterized by congenital ocular dysplasia with eyelid malformation. The pathogenicity of mutations in genes encoding components of the FRAS1/FREM protein complex is well established, but the underlying pathomechanisms of this disease are still unclear. In the previo...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zhang, Xiayin, Wang, Ruixin, Wang, Ting, Zhang, Xulin, Dongye, Meimei, Wang, Dongni, Wang, Jinghui, Li, Wangting, Wu, Xiaohang, Lin, Duoru, Lin, Haotian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820765/
https://ncbi.nlm.nih.gov/pubmed/33490088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.625492
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