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Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is the most common and severe type of interstitial lung disease for which current treatments display limited efficacy. IPF is largely driven by host-derived danger signals released upon recurrent local tissue damage. Here we explored the roles of self-DNA and stim...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Savigny, Florence, Schricke, Corinne, Lacerda-Queiroz, Norinne, Meda, Mélanie, Nascimento, Mégane, Huot-Marchand, Sarah, Da Gama Monteiro, Felipe, Ryffel, Bernhard, Gombault, Aurélie, Le Bert, Marc, Couillin, Isabelle, Riteau, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820752/
https://ncbi.nlm.nih.gov/pubmed/33488589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.588799
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