Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia

Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria and a potent inflammatory stimulus for the innate immune response via toll-like receptor (TLR) 4 activation. Type 2 diabetes is associated with changes in gut microbiota and impaired intestinal barrier func...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Kurita, Naohide, Yamashiro, Kazuo, Kuroki, Takuma, Tanaka, Ryota, Urabe, Takao, Ueno, Yuji, Miyamoto, Nobukazu, Takanashi, Masashi, Shimura, Hideki, Inaba, Toshiki, Yamashiro, Yuichiro, Nomoto, Koji, Matsumoto, Satoshi, Takahashi, Takuya, Tsuji, Hirokazu, Asahara, Takashi, Hattori, Nobutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820690/
https://ncbi.nlm.nih.gov/pubmed/31910709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19899577
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