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Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ(+/−) mice
The receptor tyrosine kinase PDGFRβ is essential for pericyte migration to the endothelium. In mice lacking one allele of PDGFRβ (PDGFRβ(+/−)), previous reports have described an age-dependent loss of pericytes in the brain, leading to cerebrovascular dysfunction and subsequent neurodegeneration rem...
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| Publicado no: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7820684/ https://ncbi.nlm.nih.gov/pubmed/31987006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19900543 |
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