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From fuzziness to precision medicine: on the rapidly evolving proteomics with implications in mitochondrial connectivity to rare human disease

Mitochondrial (mt) dysfunction is linked to rare diseases (RDs) such as respiratory chain complex (RCC) deficiency, MELAS, and ARSACS. Yet, how altered mt protein networks contribute to these ailments remains understudied. In this perspective article, we identified 21 mt proteins from public reposit...

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Podrobná bibliografie
Vydáno v:iScience
Hlavní autoři: Aly, Khaled A., Moutaoufik, Mohamed Taha, Phanse, Sadhna, Zhang, Qingzhou, Babu, Mohan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820543/
https://ncbi.nlm.nih.gov/pubmed/33521598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102030
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