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Hyperglycemia-induced VEGF and ROS production in retinal cells is inhibited by the mTOR inhibitor, rapamycin

Determine the impact of the mTOR inhibitor, rapamycin, on the hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and the production of reactive oxygen species (ROS) in retinal cells. Rats made hyperglycemic for 8 weeks by streptozotocin, as well as control rats, received i...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kida, Teruyo, Oku, Hidehiro, Osuka, Sho, Horie, Taeko, Ikeda, Tsunehiko
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820225/
https://ncbi.nlm.nih.gov/pubmed/33479328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81482-3
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