Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance

BACKGROUND/AIMS: The role of hepatitis B virus (HBV) integration into the host genome in hepatocarcinogenesis following hepatitis B surface antigen (HBsAg) seroclearance remains unknown. Our study aimed to investigate and characterize HBV integration events in chronic hepatitis B (CHB) patients who...

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Dettagli Bibliografici
Pubblicato in:Clin Mol Hepatol
Autori principali: Jang, Jeong Won, Kim, Jin Seoub, Kim, Hye Seon, Tak, Kwon Yong, Nam, Heechul, Sung, Pil Soo, Bae, Si Hyun, Choi, Jong Young, Yoon, Seung Kew, Roberts, Lewis R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Association for the Study of the Liver 2021
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820213/
https://ncbi.nlm.nih.gov/pubmed/33317255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3350/cmh.2020.0115
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