The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals

Circular RNAs (circRNAs) represent an abundant and conserved entity of non-coding RNAs; however, the principles of biogenesis are currently not fully understood. Here, we identify two factors, splicing factor proline/glutamine rich (SFPQ) and non-POU domain-containing octamer-binding protein (NONO),...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Stagsted, Lotte Victoria Winther, O'Leary, Eoghan Thomas, Ebbesen, Karoline Kragh, Hansen, Thomas Birkballe
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Chromosomes and Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819710/
https://ncbi.nlm.nih.gov/pubmed/33476259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63088
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