Blood-based extracellular matrix biomarkers as predictors of survival in patients with metastatic pancreatic ductal adenocarcinoma receiving pegvorhyaluronidase alfa

BACKGROUND: Extensive extracellular matrix (ECM) remodeling is a hallmark of metastatic pancreatic ductal adenocarcinoma (mPDA). We investigated fragments of collagen types III (C3M, PRO-C3), VI (PRO-C6), and VIII (C8-C), and versican (VCANM) in plasma as biomarkers for predicting progression-free s...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Wang, Song, Bager, Cecilie L., Karsdal, Morten A., Chondros, Dimitrios, Taverna, Darin, Willumsen, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819178/
https://ncbi.nlm.nih.gov/pubmed/33478521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02701-z
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