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Synthesis, Anticancer Evaluation, Computer-Aided Docking Studies, and ADMET Prediction of 1,2,3-Triazolyl-Pyridine Hybrids as Human Aurora B Kinase Inhibitors

[Image: see text] A novel series of 1,2,3-triazolyl-pyridine hybrids were prepared through the reaction of the triazole derivative (1) with the appropriate aldehyde (2a–g) and malononitrile or ethyl cyanoacetate in the presence of ammonium acetate in refluxed acetic acid. The chemical composition of...

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Bibliografiset tiedot
Julkaisussa:ACS Omega
Päätekijät: Rashdan, Huda R.M., Shehadi, Ihsan A., Abdelmonsef, Abobakr H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2021
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818638/
https://ncbi.nlm.nih.gov/pubmed/33490804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05116
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