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A homozygous truncating variant in CCDC186 in an individual with epileptic encephalopathy

Coiled‐Coil Domain Containing Protein 186 (CCDC186) is hypothesized to play an important role in the biogenesis of dense‐core vesicles in neurons and endocrine cells. Biallelic loss‐of‐function variants in the encoding gene CCDC186 have been suggested as a candidate gene for a neurodevelopmental phe...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Brugger, Melanie, Becker‐Dettling, Fiona, Brunet, Theresa, Strom, Tim, Meitinger, Thomas, Lurz, Eberhard, Borggraefe, Ingo, Wagner, Matias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818090/
https://ncbi.nlm.nih.gov/pubmed/33259146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51260
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