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Pan-Cancer Analysis of Head-to-Head Gene Pairs in Terms of Transcriptional Activity, Co-expression and Regulation

BACKGROUND: Head-to-Head (H2H) gene pairs are regulated by bidirectional promoters and divergently transcribed from opposite DNA strands with transcription start sites (TSSs) separated within 1 kb. H2H organization is ancient and conserved, and H2H pairs tend to exhibit similar expression patterns....

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Bibliografiska uppgifter
I publikationen:Front Genet
Huvudupphovsmän: Chen, Yunqin, Li, Hong, Li, Yuan-Yuan, Li, Yixue
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817982/
https://ncbi.nlm.nih.gov/pubmed/33488665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.560997
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