Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling

G Protein Suppressor 2 (GPS2) is a multifunctional protein that exerts important roles in inflammation and metabolism in adipose, liver, and immune cells. GPS2 has recently been identified as a significantly mutated gene in breast cancer and other malignancies and proposed to work as a putative tumo...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Chan, Stefanie, Smith, Emma, Gao, Yuan, Kwan, Julian, Blum, Benjamin C., Tilston-Lunel, Andrew M., Turcinovic, Isabella, Varelas, Xaralabos, Cardamone, Maria Dafne, Monti, Stefano, Emili, Andrew, Perissi, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817781/
https://ncbi.nlm.nih.gov/pubmed/33490071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.608044
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