Pragmatic, open-label, single-center, randomized, phase II clinical trial to evaluate the efficacy and safety of methylprednisolone pulses and tacrolimus in patients with severe pneumonia secondary to COVID-19: The TACROVID trial protocol

INTRODUCTION: Some COVID-19 patients evolve to severe lung injury and systemic hyperinflammatory syndrome triggered by both the coronavirus infection and the subsequent host-immune response. Accordingly, the use of immunomodulatory agents has been suggested but still remains controversial. Our worki...

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Publicado en:Contemp Clin Trials Commun
Autores principales: Solanich, X., Antolí, A., Padullés, N., Fanlo-Maresma, M., Iriarte, A., Mitjavila, F., Capdevila, O., Molina, M., Sabater, J., Bas, J., Mensa-Vilaró, A., Niubó, J., Calvo, N., Bolivar, S., Rigo-Bonnin, R., Arregui, L., Tebé, C., Hereu, P., Videla, S., Corbella, X.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817439/
https://ncbi.nlm.nih.gov/pubmed/33495742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2021.100716
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