Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways

Candidiasis, aspergillosis, and mucormycosis cause the majority of nosocomial fungal infections in immunocompromised patients. Using an unbiased transcriptional profiling in PBMCs exposed to the fungal species causing these infections, we found a core host response in healthy individuals that may go...

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發表在:Comput Struct Biotechnol J
Main Authors: Bruno, Mariolina, Dewi, Intan M.W., Matzaraki, Vicky, ter Horst, Rob, Pekmezovic, Marina, Rösler, Berenice, Groh, Laszlo, Röring, Rutger J., Kumar, Vinod, Li, Yang, Carvalho, Agostinho, Netea, Mihai G., Latgé, Jean-Paul, Gresnigt, Mark S., van de Veerdonk, Frank L.
格式: Artigo
語言:Inglês
出版: Research Network of Computational and Structural Biotechnology 2020
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817431/
https://ncbi.nlm.nih.gov/pubmed/33510868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.036
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