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Genome-wide surveillance of transcription errors in response to genotoxic stress

Mutagenic compounds are a potent source of human disease. By inducing genetic instability, they can accelerate the evolution of human cancers or lead to the development of genetically inherited diseases. Here, we show that in addition to genetic mutations, mutagens are also a powerful source of tran...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Fritsch, C., Gout, J.-F., Haroon, S., Towheed, A., Chung, C., LaGosh, J., McGann, E., Zhang, X., Song, Y., Simpson, S., Danthi, P. S., Benayoun, B. A., Wallace, D., Thomas, K., Lynch, M., Vermulst, M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817157/
https://ncbi.nlm.nih.gov/pubmed/33443141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004077118
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