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Dynamic bistable switches enhance robustness and accuracy of cell cycle transitions

Bistability is a common mechanism to ensure robust and irreversible cell cycle transitions. Whenever biological parameters or external conditions change such that a threshold is crossed, the system abruptly switches between different cell cycle states. Experimental studies have uncovered mechanisms...

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Publicat a:PLoS Comput Biol
Autors principals: Rombouts, Jan, Gelens, Lendert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817062/
https://ncbi.nlm.nih.gov/pubmed/33411761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008231
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