Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

With the advent of potent second-line anti-androgen therapy, we and others have observed an increased incidence of androgen receptor (AR)-null small cell or neuroendocrine prostate cancer (SCNPC) in metastatic castration-resistant prostate cancer (mCRPC). Our study was designed to determine the effe...

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Bibliographic Details
Published in:PLoS One
Main Authors: Labrecque, Mark P., Brown, Lisha G., Coleman, Ilsa M., Nguyen, Holly M., Lin, Daniel W., Corey, Eva, Nelson, Peter S., Morrissey, Colm
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817027/
https://ncbi.nlm.nih.gov/pubmed/33471819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245602
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