In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ

Adult T cell leukemia (ATL) is an aggressive malignancy secondary to chronic infection by the human T-cell leukemia virus type 1 (HTLV-1) infection. Two viral proteins, Tax and HBZ, play central roles in ATL leukemogenesis. Tax expression transforms T cells in vitro and induces ATL-like disease in m...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Akkouche, Abdou, Moodad, Sara, Hleihel, Rita, Skayneh, Hala, Chambeyron, Séverine, El Hajj, Hiba, Bazarbachi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817025/
https://ncbi.nlm.nih.gov/pubmed/33471856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009219
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