The mutation of BCOR is highly recurrent and oncogenic in mature T-cell lymphoma

BACKGROUND: BCOR acts as a corepressor of BCL6, a potent oncogenic protein in cancers of the lymphoid lineage. We have found the recurrent somatic mutation of BCOR occurred in mature T-cell lymphoma (TCL). The role of BCOR mutation in lymphoid malignancies is unknown. METHODS: Lymphoma patient sampl...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Kang, Jin Hyun, Lee, Seung Ho, Lee, Jawon, Choi, Murim, Cho, Junhun, Kim, Seok Jin, Kim, Won Seog, Ko, Young Hyeh, Yoo, Hae Yong
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816311/
https://ncbi.nlm.nih.gov/pubmed/33468080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07806-8
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