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Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney
Hypomagnesaemia is a common feature of renal Na(+) wasting disorders such as Gitelman and EAST/SeSAME syndrome. These genetic defects specifically affect Na(+) reabsorption in the distal convoluted tubule, where Mg(2+) reabsorption is tightly regulated. Apical uptake via TRPM6 Mg(2+) channels and ba...
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| Pubblicato in: | Acta Physiol (Oxf) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7816272/ https://ncbi.nlm.nih.gov/pubmed/32603001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13528 |
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