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From SAR Diagnostics to Compound Design: Development Chronology of the Compound Optimization Monitor (COMO) Method

In medicinal chemistry, compound optimization largely depends on chemical knowledge, experience, and intuition, and progress in hit‐to‐lead and lead optimization projects is difficult to estimate. Accordingly, approaches are sought after that aid in assessing the odds of success with an optimization...

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Detalhes bibliográficos
Publicado no:Mol Inform
Main Authors: Yonchev, Dimitar, Vogt, Martin, Bajorath, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816267/
https://ncbi.nlm.nih.gov/pubmed/32282989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.202000046
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