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Activation of WNT signaling restores the facial deficits in a zebrafish with defects in cholesterol metabolism

Inborn errors of cholesterol metabolism occur as a result of mutations in the cholesterol synthesis pathway (CSP). Although mutations in the CSP cause a multiple congenital anomaly syndrome, craniofacial abnormalities are a hallmark phenotype associated with these disorders. Previous studies have es...

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Podrobná bibliografie
Vydáno v:Genesis
Hlavní autoři: Castro, Victoria L., Reyes‐Nava, Nayeli G., Sanchez, Brianna B., Gonzalez, Cesar G., Paz, David, Quintana, Anita M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816230/
https://ncbi.nlm.nih.gov/pubmed/33197123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23397
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