IS26-mediated amplification of bla(OXA-1) and bla(CTX-M-15) with concurrent outer membrane porin disruption associated with de novo carbapenem resistance in a recurrent bacteraemia cohort

BACKGROUND: Approximately half of clinical carbapenem-resistant Enterobacterales (CRE) isolates lack carbapenem-hydrolysing enzymes and develop carbapenem resistance through alternative mechanisms. OBJECTIVES: To elucidate development of carbapenem resistance mechanisms from clonal, recurrent ESBL-p...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Shropshire, William C, Aitken, Samuel L, Pifer, Reed, Kim, Jiwoong, Bhatti, Micah M, Li, Xiqi, Kalia, Awdhesh, Galloway-Peña, Jessica, Sahasrabhojane, Pranoti, Arias, Cesar A, Greenberg, David E, Hanson, Blake M, Shelburne, Samuel A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816169/
https://ncbi.nlm.nih.gov/pubmed/33164081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa447
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