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Washing with alkaline solutions in protein A purification improves physicochemical properties of monoclonal antibodies
Protein A affinity chromatography has been widely used for both laboratory scale purification and commercial manufacturing of monoclonal antibodies and Fc-fusion proteins. Protein A purification is specific and efficient. However, there still remain several issues to be addressed, such as incomplete...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7815873/ https://ncbi.nlm.nih.gov/pubmed/33469121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81366-6 |
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