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The program of renal fibrogenesis is controlled by microRNAs regulating oxidative metabolism

Excessive accumulation of extracellular matrix (ECM) is the hallmark of fibrotic diseases. In the kidney, it is the final common pathway of prevalent diseases, leading to chronic renal failure. While cytokines such as TGF-β play a fundamental role in myofibroblast transformation, recent work has sho...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Miguel, Verónica, Ramos, Ricardo, García-Bermejo, Laura, Rodríguez-Puyol, Diego, Lamas, Santiago
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815809/
https://ncbi.nlm.nih.gov/pubmed/33465566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101851
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