AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Although activator of HSP90 ATPase activity 1 (AHA1) is reported to be a potential oncogene, its role in osteosarcoma progression remains largely unclear. Since metabolism reprogramming is involved in tumo...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Zheng, Diwei, Liu, Weihai, Xie, Wenlin, Huang, Guanyu, Jiang, Qiwei, Yang, Yang, Huang, Jiarong, Xing, Zihao, Yuan, Mengling, Wei, Mengning, Li, Yao, Yin, Junqiang, Shen, Jingnan, Shi, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815748/
https://ncbi.nlm.nih.gov/pubmed/33468990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00387-1
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