Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation, such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms regulating CSF clearance during the postnatal critical period are unclear. Here, we show that CSF K(+), accompanied by wa...

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Vydáno v:Nat Commun
Hlavní autoři: Xu, Huixin, Fame, Ryann M., Sadegh, Cameron, Sutin, Jason, Naranjo, Christopher, Della Syau, Cui, Jin, Shipley, Frederick B., Vernon, Amanda, Gao, Fan, Zhang, Yong, Holtzman, Michael J., Heiman, Myriam, Warf, Benjamin C., Lin, Pei-Yi, Lehtinen, Maria K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815709/
https://ncbi.nlm.nih.gov/pubmed/33469018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20666-3
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