Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration

Biomimetic bone tissue engineering strategies partially recapitulate development. We recently showed functional restoration of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates featuring localized morphogen presentation with delayed in vivo mechanical loading. Possib...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Herberg, Samuel, Varghai, Daniel, Alt, Daniel S., Dang, Phuong N., Park, Honghyun, Cheng, Yuxuan, Shin, Jung-Youn, Dikina, Anna D., Boerckel, Joel D., Rolle, Marsha W., Alsberg, Eben
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815708/
https://ncbi.nlm.nih.gov/pubmed/33469154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01576-y
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