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Mathematical modeling of depressive disorders: Circadian driving, bistability and dynamical transitions
The hypothalamus–pituitary–adrenal (HPA) axis is a key neuroendocrine system implicated in stress response, major depression disorder, and post-traumatic stress disorder. We present a new, compact dynamical systems model for the response of the HPA axis to external stimuli, representing stressors or...
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| 出版年: | Comput Struct Biotechnol J |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Research Network of Computational and Structural Biotechnology
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7815682/ https://ncbi.nlm.nih.gov/pubmed/33510869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.10.035 |
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