Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1

Electronic pacemakers still face major shortcomings that are largely intrinsic to their hardware-based design. Radical improvements can potentially be generated by gene or cell therapy-based biological pacemakers. Our previous work identified adenoviral gene transfer of Hcn2 and SkM1, encoding a “fu...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Végh, Anna M. D., Verkerk, Arie O., Cócera Ortega, Lucía, Wang, Jianan, Geerts, Dirk, Klerk, Mischa, Lodder, Kirsten, Nobel, Ruby, Tijsen, Anke J., Devalla, Harsha D., Christoffels, Vincent M., Medina-Ramírez, Max, Smits, Anke M., Tan, Hanno L., Wilders, Ronald, Goumans, Marie José T. H., Boink, Gerard J. J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815531/
https://ncbi.nlm.nih.gov/pubmed/33488393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.588679
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