Overcoming TKI resistance in fusion-driven NSCLC: new generation inhibitors and rationale for combination strategies

During the last several years, multiple gene rearrangements with oncogenic potential have been described in NSCLC, identifying specific clinic-pathological subgroups of patients that benefit from a targeted therapeutic approach, including anaplastic lymphoma kinase (ALK), c-ros protooncogene 1 (ROS1...

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Bibliografiske detaljer
Udgivet i:Transl Lung Cancer Res
Main Authors: Russo, Alessandro, Cardona, Andrés F., Caglevic, Christian, Manca, Paolo, Ruiz-Patiño, Alejandro, Arrieta, Oscar, Rolfo, Christian
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2020
Fag:
Review Article on Looking for Chimeras in NSCLC: Widen Therapeutic Options Targeting Oncogenic Fusions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815353/
https://ncbi.nlm.nih.gov/pubmed/33489820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-2019-cnsclc-06
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