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Central nervous system metastases and oligoprogression during treatment with tyrosine kinase inhibitors in oncogene-addicted non-small cell lung cancer: how to treat and when?

Up to 70% of non-small cell lung cancer (NSCLC) patients develop central nervous system (CNS) metastases during the course of their disease, especially those with oncogenic drivers treated with a first-generation tyrosine kinase inhibitor (TKI), because of the relatively poor CNS penetration. CNS me...

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Библиографические подробности
Опубликовано в: :Transl Lung Cancer Res
Главные авторы: Schoenmaekers, Janna Josephus Anna Oda, Paats, Marthe Sentijna, Dingemans, Anne-Marie Clasina, Hendriks, Lizza Elisabeth Lucia
Формат: Artigo
Язык:Inglês
Опубликовано: AME Publishing Company 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815343/
https://ncbi.nlm.nih.gov/pubmed/33489821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-459
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