How selecting best upfront therapy for metastatic disease?—Focus on ROS1-rearranged disease

ROS proto-oncogene 1 (ROS1) rearrangements defines a distinct group of non-small cell lung cancer (NSCLC), mainly represented by younger subjects, never smokers and with adenocarcinoma histology. Fusions involving ROS1 gene are present in 1-2% of lung adenocarcinomas and other solid tumors. Identifi...

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Bibliographic Details
Published in:Transl Lung Cancer Res
Main Authors: Landi, Lorenza, Cappuzzo, Federico
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2020
Subjects:
Review Article on Looking for Review Article on Looking for Chimeras in NSCLC: Widen Therapeutic Options Targeting Oncogenic Fusions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815342/
https://ncbi.nlm.nih.gov/pubmed/33489827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-1109
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