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A reduction of primary cilia but not hedgehog signaling disrupts morphogenesis in testicular organoids

Most mammalian cells possess a single, non-motile primary cilium that plays an important role in mediating cellular signaling pathways, such as Hedgehog (Hh) signaling. Primary cilia are present on testicular somatic cells and demonstrate a temporal expression during development; however, their role...

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Bibliografische gegevens
Gepubliceerd in:Cell Tissue Res
Hoofdauteurs: Goldsmith, Taylor M., Sakib, Sadman, Webster, Dennis, Carlson, Daniel F., der Hoorn, Frans Van, Dobrinski, Ina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815324/
https://ncbi.nlm.nih.gov/pubmed/31900662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-019-03121-8
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