Mesenchymal Stem Cells Enhance Therapeutic Effect and Prevent Adverse Gastrointestinal Reaction of Methotrexate Treatment in Collagen-Induced Arthritis

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by articular destruction and functional loss. Methotrexate (MTX) is effective in RA treatment. However, MTX induces several adverse events and 20%-30% of patients do not respond to MTX. Thus, it is urgent to enhance the therape...

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Bibliografiske detaljer
Udgivet i:Stem Cells Int
Main Authors: Zhai, Qiming, Dong, Jiayi, Zhang, Xuesi, He, Xiaoning, Fei, Dongdong, Jin, Yan, Li, Bei, Jin, Fang
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814936/
https://ncbi.nlm.nih.gov/pubmed/33505476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8850820
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