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Plasma levels of a methadone constant rate infusion and their corresponding effects on thermal and mechanical nociceptive thresholds in dogs

BACKGROUND: The present study aimed to collect pharmacokinetic data of a methadone continuous rate infusion (CRI) and to investigate its effect on mechanical and thermal nociceptive thresholds. Seven, 47 to 54 months old beagle dogs, weighing 9.8 to 21.2 kg, were used in this experimental, randomize...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Amon, T., Kästner, S. B. R., Kietzmann, M., Tünsmeyer, J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814539/
https://ncbi.nlm.nih.gov/pubmed/33461553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02735-3
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