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Pair consensus decoding improves accuracy of neural network basecallers for nanopore sequencing

We develop a general computational approach for improving the accuracy of basecalling with Oxford Nanopore’s 1D(2) and related sequencing protocols. Our software PoreOver (https://github.com/jordisr/poreover) finds the consensus of two neural networks by aligning their probability profiles, and is c...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Silvestre-Ryan, Jordi, Holmes, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814537/
https://ncbi.nlm.nih.gov/pubmed/33468205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02255-1
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