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T(reg) cell-based therapies: challenges and perspectives

Cellular therapies using regulatory T (T(reg)) cells are currently undergoing clinical trials for the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease. In this Review, we discuss the biology of T(reg) cells and describe new efforts in T(reg) cell engineering to en...

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Pubblicato in:Nat Rev Immunol
Autori principali: Raffin, Caroline, Vo, Linda T., Bluestone, Jeffrey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814338/
https://ncbi.nlm.nih.gov/pubmed/31811270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0232-6
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