Suppression of Hypertrophy During in vitro Chondrogenesis of Cocultures of Human Mesenchymal Stem Cells and Nasal Chondrocytes Correlates With Lack of in vivo Calcification and Vascular Invasion

OBJECTIVE: Human nasal septal chondrocytes (NC) are a promising minimally invasive derivable chondrogenic cell source for cartilage repair. However, the quality of NC-derived cartilage is variable between donors. Coculture of NC with mesenchymal stem cells (MSCs) mitigates the variability but with u...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Anderson-Baron, Matthew, Liang, Yan, Kunze, Melanie, Mulet-Sierra, Aillette, Osswald, Martin, Ansari, Khalid, Seikaly, Hadi, Adesida, Adetola B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813892/
https://ncbi.nlm.nih.gov/pubmed/33469528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.572356
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