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Actinobacillus pleuropneumoniae exotoxin ApxI induces cell death via attenuation of FAK through LFA-1

ApxI exotoxin is an important virulence factor derived from Actinobacillus pleuropneumoniae that causes pleuropneumonia in swine. Here, we investigate the role of lymphocyte function-associated antigen 1 (LFA-1, CD11a/CD18), a member of the β(2) integrin family, and the involvement of the integrin s...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Li, Siou-Cen, Cheng, Yu-Tsen, Wang, Ching-Yang, Wu, Jia-Ying, Chen, Zeng-Weng, Wang, Jyh-Perng, Lin, Jiunn-Horng, Hsuan, Shih-Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813829/
https://ncbi.nlm.nih.gov/pubmed/33462305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81290-9
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