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Randomised phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer (OCTOVA): a study protocol

INTRODUCTION: Patients relapsing within 12 months of platinum-based chemotherapy usually have a poorer response to subsequent treatments. To date, extensive research into the mechanism of resistance to platinum agents in the treatment of ovarian cancer has not resulted in improved responses or longe...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Mansouri, Anita, McGregor, Naomi, Dunn, Rachel, Dobbie, Sam, Holmes, Jane, Collins, Linda, Nicum, Shibani
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813404/
https://ncbi.nlm.nih.gov/pubmed/33452192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-041463
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