Á lódáil...
Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms
During protein synthesis, nonsense mutations, resulting in premature stop codons (PSCs), produce truncated, inactive protein products. Such defective gene products give rise to many diseases, including cystic fibrosis, Duchenne muscular dystrophy (DMD), and some cancers. Small molecule nonsense supp...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812769/ https://ncbi.nlm.nih.gov/pubmed/33414181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020599118 |
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