Conserved missense variant in ALDH1A3 ortholog impairs fecundity in C. elegans

Accumulating evidence demonstrates that mutations in ALDH1A3 (the aldehyde dehydrogenase 1 family, member A3) are associated with developmental defects. The ALDH1A3 enzyme catalyzes retinoic acid biosynthesis and is essential to patterning and neuronal differentiation in the development of embryonic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:MicroPubl Biol
Prif Awduron: Wong, Wan-Rong, Maher, Shayda, Oh, Jun Young, Brugman, Katherine I, Gharib, Shahla, Sternberg, Paul W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Caltech Library 2021
Pynciau:
New Finding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812383/
https://ncbi.nlm.nih.gov/pubmed/33474529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17912/micropub.biology.000357
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