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Extracellular vesicles from skin precursor-derived Schwann cells promote axonal outgrowth and regeneration of motoneurons via Akt/mTOR/p70S6K pathway

BACKGROUND: Skin precursor-derived Schwann cells (SKP-SCs) have been shown to benefit the recovery of spinal cord injury (SCI) and peripheral nerve injury (PNI) with motor dysfunction. However, the effect of extracellular vesicles (EVs) from SKP-SCs responsible for neuroregeneration remains unknown....

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Podrobná bibliografie
Vydáno v:Ann Transl Med
Hlavní autoři: Wu, Xia, Wang, Liting, Cong, Meng, Shen, Mi, He, Qianru, Ding, Fei, Shi, Haiyan
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812244/
https://ncbi.nlm.nih.gov/pubmed/33490152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5965
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