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Neferine induces p38 MAPK/JNK1/2 activation to modulate melanoma proliferation, apoptosis, and oxidative stress

BACKGROUND: Melanoma is a malignant skin cancer that has a poor prognosis in advanced patients. The aim of the present study was to investigate the antitumor role of neferine in melanoma. METHODS: A375 and C32 cells were selected as research vectors in vitro. Cell counting Kit-8, 5-ethynyl-2’-deoxyu...

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Publicat a:Ann Transl Med
Autors principals: Xie, Jun, Chen, Ming-Hui, Ying, Chuan-Peng, Chen, Ming-Yi
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812205/
https://ncbi.nlm.nih.gov/pubmed/33490155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-7201
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