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Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs

A vaccine providing both powerful Ab and cross-reactive T cell immune responses against influenza viruses would be beneficial for both humans and pigs. In this study, we evaluated i.m., aerosol (Aer), and simultaneous systemic and respiratory immunization (SIM) by both routes in Babraham pigs, using...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Martini, Veronica, Paudyal, Basu, Chrun, Tiphany, McNee, Adam, Edmans, Matthew, Atangana Maze, Emmanuel, Clark, Beckie, Nunez, Alejandro, Dolton, Garry, Sewell, Andrew, Beverley, Peter, MacLoughlin, Ronan, Townsend, Alain, Tchilian, Elma
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812058/
https://ncbi.nlm.nih.gov/pubmed/33328212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001086
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