A small molecule interacts with pMAC-derived hydroperoxide reductase and enhances the activity of aminoglycosides

The threat of antimicrobial resistance calls for more efforts in basic science, drug discovery, and clinical development, particularly gram-negative carbapenem-resistant pathogens. We sought to identify novel antibacterial agents against Acinetobacter baumannii ATCC19606 using whole cell-based scree...

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Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Hui, Zhen, Liu, Shiyi, Cui, Ruiqin, Zhou, Biao, Hu, Chunxia, Zhang, Min, Deng, Qiuyang, Cheng, Shumin, Luo, Yutian, Chen, Huaisheng, Wu, Jinsong, Lu, Yuemei, Liu, Xueyan, Dai, Lingyun, Huang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811946/
https://ncbi.nlm.nih.gov/pubmed/33456052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41429-020-00401-2
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