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Inhibition of Rho-kinase improves response to deep inspiration in ovalbumin-sensitized guinea pigs

OBJECTIVE(S): The modulatory effect of deep inspiration (DI) on airway constriction is impaired in asthma. However, mechanisms underlying this impairment are not clear. Since there is evidence indicating that Rho-kinase activation mediates force maintenance under oscillatory strain, we investigated...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Iran J Basic Med Sci
Κύριοι συγγραφείς: Pazhoohan, Saeed, Aref, Ehsan, Zare, Leila, Dehghan, Samaneh, Javan, Mohammad, Hajizadeh, Sohrab, Raoufy, Mohammad Reza
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Mashhad University of Medical Sciences 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811819/
https://ncbi.nlm.nih.gov/pubmed/33489033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.46258.10683
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