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Inhibition of Rho-kinase improves response to deep inspiration in ovalbumin-sensitized guinea pigs

OBJECTIVE(S): The modulatory effect of deep inspiration (DI) on airway constriction is impaired in asthma. However, mechanisms underlying this impairment are not clear. Since there is evidence indicating that Rho-kinase activation mediates force maintenance under oscillatory strain, we investigated...

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Bibliografiska uppgifter
I publikationen:Iran J Basic Med Sci
Huvudupphovsmän: Pazhoohan, Saeed, Aref, Ehsan, Zare, Leila, Dehghan, Samaneh, Javan, Mohammad, Hajizadeh, Sohrab, Raoufy, Mohammad Reza
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mashhad University of Medical Sciences 2020
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811819/
https://ncbi.nlm.nih.gov/pubmed/33489033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.46258.10683
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